The Social and Behavioral Research Branch (SBRB) conducts a broad array of research in applying new genomic discovery to improve health and clinical care aligned with the four themes below. The branch was founded just over 10 years ago.
Themes of Research
We aim to untangle genomic factors that impact brain development and behavior, and the potential clinical use of these discoveries. We evaluate approaches for communicating genomic information to patients and clients that optimize health outcomes. Further, we study factors that influence a variety of health-related decision-making in the context of genomic testing and support services, and patient responses to receipt of genomic information.
We evaluate community-based educational approaches that leverage social influence to improve knowledge of genomic information and engagement in risk-reducing behaviors. Our work also considers how genomic information flows through family systems, and how families respond to shared disease risk. Research in the SBRB further explores how genomics shapes social systems, and how the social environment, including social stigma, impacts health.
We conduct research to evaluate the use of genomic knowledge and technologies to decrease health disparities and enable access to these technologies among underserved populations. For example, our work considers how genomic discoveries intersect with racial, ethnic and social identities. This research considers health disparities both within the clinical setting, with a focus on patient-provider interactions, and community settings. Additionally, we evaluate health promotion interventions that include genomic information with under-resourced, stigmatized and marginalized groups.
Methods and Measures
We develop novel methodologies for integrating complex data relating to genomics, social processes, behavior and the brain. For example, we are examining how common and rare genetic variations impact the development of the brain and behavior. We are developing novel methods to quantify how genomic information impacts the flow of information and support across complex social systems. Finally, we apply innovative technologies such as virtual reality and state of the art neuroimaging to common clinical problems.7